I do agree that a reinstallation is a good idea at this point. What you should backup is your database, but I don't think you should backup changes settings etc. since it's likely that the problem could be related to the settings files. Backing up your database is easy, all you need to do is to go to Database -> Backup Database and then keep the file in a safe location.
Just drop me a PM with your registered e-mail address and I'll send you your key.
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